FoxP1 “Tspans” Quiescence and Activation of Mammary Stem Cells
Wrenn ED, Cheung KJ.
Dev Cell. 2018 Dec 3;47(5):539-540. doi: 10.1016/j.devcel.2018.11.017.
Abstract
Stem cells can enter a reversible cell-cycle arrest state termed quiescence. In this issue of Developmental Cell, Fu et al. report that the transcription factor FoxP1 is necessary for postnatal mammary gland development and relieves Tspan8-dependent quiescence in basal mammary stem cells.