Migrating cells have key functions in shaping tissues during development, repairing tissues after development and supporting cancer invasion and metastasis. In all these contexts, cells often maintain contact with their neighbors and move as a group, in a process termed collective migration. In this Review with colleague and developmental biologist Sally Horne-Badovinac at U. Chicago, we consider the elegant mechanisms used by collectively migrating cells in vivo to coordinate their movements and obtain directional information.
Collective migration modes in development, tissue repair and cancer
Cheung KJ*, Horne-Badovinac S*
* co-corresponding authors
Nat Rev Mol Cell Biol. 2025 Jun 5. doi: 10.1038/s41580-025-00858-9.