Therapeutic potential of targeting haploinsufficient genes in cancer

Cheung KJ, Ebert BL.

Pediatr Blood Cancer. 2009 Aug;53(2):131-2. doi: 10.1002/pbc.22019.

Abstract

Comment on Taniguchi et al. Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma. Pediatric Blood Cancer 2009.

https://doi.org/10.1002/pbc.22019