Andie successfully defends her dissertation. Congrats Andie and an end of an era!
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Andie successfully defends her dissertation
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Welcome Justin, our new MCB student
Justin Hui joins the lab as a full-time graduate student. Welcome Justin!
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Lab receives Medical Research Grant from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation
The Cheung lab receives a 3-year grant from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation to define intercellular signals utilized by triple negative breast cancer metastases. With local collaborators Pete Nelson, Nancy Davidson, and Paul Lampe, this project will develop targeted therapy approaches for blocking tumor cell cooperation important for therapy resistance and visceral metastasis.
https://www.fredhutch.org/en/news/center-news/2024/03/cheung-kleberg-cancer-cooperation.html
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Welcome Nicole and farewell Saki!
Farewell to Saki our awesome lab tech on loan from Daiichi Sankyo, and welcome Nicole our new lab tech!
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Ami’s tumor dissemination paper comes out in PNAS!
Ami’s metastasis paper comes out in PNAS today. In this study, we asked where tumor cell dissemination from. We thought the action would be at the tumor’s edge. But instead we find a role for cancer cells in the necrotic core: zones of intense cell death within tumors. Along the way, we identify a tumor-secreted protein expressed deep inside the tumor involved in regulating necrosis, CTC dissemination and metastasis. Read the paper to find out more.
Link to Hutch Center News article.
Link to Charles River Webinar on in vivo modeling of breast tumor dissemination.
Link to Hutch Science Spotlight. Thank you to David Sokolov for writing this piece!
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Lab receives Kuni Foundation Grant
The Cheung lab receives a 3-year grant from the Kuni Foundation to develop a therapeutic antibody to prevent necrosis, metastatic dissemination, and therapy resistance. Our goal for this project is to develop a therapeutic antibody that will be advanced to early phase clinical trial. We are grateful to the Kuni Foundation for their generous support!
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Beth is awarded an American Cancer Society Postdoctoral Fellowship
Beth is awarded a competitive 2-year fellowship from the American Cancer Society. Congrats Beth!
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The Cheung lab is awarded an Evergreen Fund Beyond Pilot Award
The Cheung lab is awarded a competitive Beyond Pilot Award from the Hutch Evergreen Fund to advance the commercialization potential of our technology for therapeutic targeting of necrosis. Thank you Evergreen Fund for supporting our research!
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Brad and Andie present their work at SABCS 2022
Brad, Andie, and Kevin travel to Texas to learn more about latest in breast cancer research at the San Antonio Breast Cancer Symposium and to present their work on collective invasion and signaling.
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Welcome Yuji!
Yuji Kumagai is a new postdoctoral fellow in the lab. He received his PhD from Hokkaido University in Japan. In the Cheung lab, he will work on the role of collective signaling in therapy resistance.